RX Squad frames its action around an invasion: space monsters threaten Earth, and the terran defense forces send the RX Squad into combat. Players pilot advanced ships through levels, with each ship offering different abilities. That setup gives the game a clear arcade-shooter focus, while the varied ships add a choice of play style within its straightforward rescue mission.
Survival and score shape each run. A ship must avoid both contact with monsters and crashes into the scenario, and the levels have no checkpoints. To clear a level, players must reach its end with at least a minimum number of points. Between levels, weapons can be customized with different kinds of ammunition, giving players a chance to adjust their loadout as they advance. Controls include movement, Turbo, Fire, and Special, with joystick control specified.
The Steam listing identifies RX Squad as single-player, so its level-by-level challenge is designed for solo play rather than cooperative or competitive sessions.