NBA 2K21 is a basketball simulation built around the spectacle and competition of the NBA. Its design spans on-court play, team-building, career progression, and online competition, giving players several ways to engage with basketball rather than a single-match format. The store description says multiplayer servers shut down as of December 31, 2022, and that functions requiring online servers would no longer work after that date.
On the court, the Pro Stick supports aimed jump shots and layups, while ball handling includes signature dribble moves. MyCAREER follows a MyPLAYER from high school through one of ten licensed college programs and into the professional ranks. MyTEAM takes a collecting approach: players assemble current NBA stars and legendary players, then compete with other collectors in modes that include limited-time Seasons and rewards.
The Neighborhood adds a beachside setting for one-on-one, three-on-three, and five-on-five play, alongside the Park, Pro-Am, and 2K Compete Events. The game also offers classic USA Basketball teams, while its listed categories include shared-screen PvP and co-op.