Hospital 666 casts players into an abnormal, seemingly endless hospital, where escape depends on choosing between the front and rear elevators. Its central test is observational: inspect each room for something out of place, then decide which direction to take. The game’s repeated warning to turn around when something seems strange captures its defining tension, making careful attention part of the route forward.
As players move through different rooms, they encounter anomalies and may also be pursued by monsters. The store description lists more than 100 floors, 85 unique anomalies, and five bosses, alongside Easy, Normal, and Hell difficulty modes. It also describes automatic saving on each floor and designated checkpoint floors, giving the journey a floor-by-floor structure. Those details frame the game as a sequence of unsettling discoveries and escape decisions rather than a conventional action campaign.
Hospital 666 supports solo play as well as online cooperation for two to four people. Its elevator choices, room-to-room inspection, and possible monster encounters define the experience those different play arrangements serve.