In Destroy All Humans!, players take the role of Crypto-137, an alien invader terrorizing 1950s Earth. His campaign sets a comic, destructive premise against the era’s fragile democracy: harvest DNA, bring down the US government, and make the humans’ predicament part of the joke. The game is described as a remake, faithfully rebuilt from scratch, of a cult-classic alien-invasion adventure.
Its action mixes alien weapons and psychic powers with a flying saucer, giving Crypto several ways to disrupt human life. Psychokinesis sends enemies flying or hurls objects, while disguise lets him pose as a human to infiltrate political institutions. Players can roam explorable cities in 1950s America with a jetpack, then turn the saucer against the surrounding architecture. The Anal Probe Gun adds an intentionally irreverent touch to the weaponry, and the game also includes the restored Lost Mission of Area 42.
The store lists Destroy All Humans! as single-player, so its player-count context is a solo adventure rather than a cooperative or competitive multiplayer match. That format fits a story built around one alien protagonist, blending exploration, infiltration, psychic mischief, and large-scale destruction. The documented design points to a focused action-adventure experience whose distinctive appeal is the contrast between Crypto’s outlandish arsenal and the familiar setting of 1950s America.